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Elaine Westrick Selected Research

EC145

3/2014Folate-vinca alkaloid conjugates for cancer therapy: a structure-activity relationship.
2/2011Reducing undesirable hepatic clearance of a tumor-targeted vinca alkaloid via novel saccharopeptidic modifications.
9/2009In vivo structural activity and optimization studies of folate-tubulysin conjugates.
10/2007Comparative preclinical activity of the folate-targeted Vinca alkaloid conjugates EC140 and EC145.
5/2007Preclinical evaluation of EC145, a folate-vinca alkaloid conjugate.

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Elaine Westrick Research Topics

Disease

20Neoplasms (Cancer)
01/2020 - 03/2005
4Inflammation (Inflammations)
10/2021 - 04/2011
2Experimental Arthritis
07/2015 - 04/2011
2Rheumatoid Arthritis
07/2015 - 04/2011
2Hypersensitivity (Allergy)
09/2009 - 09/2007
2Weight Loss (Weight Reduction)
07/2007 - 05/2007
1Cytokine Release Syndrome
10/2021
1Osteosarcoma (Osteogenic Sarcoma)
01/2019
1Acute Myeloid Leukemia (Acute Myelogenous Leukemia)
01/2019
1Polycystic Kidney Diseases (Polycystic Kidney Disease)
01/2019
1Encephalomyelitis (Myeloencephalitis)
01/2014
1Uveitis
01/2014
1Arthritis (Polyarthritis)
04/2011
1Constipation
02/2011
1Anaphylaxis (Anaphylactic Shock)
09/2009
1Lymphoma (Lymphomas)
05/2007
1Carcinoma (Carcinomatosis)
03/2005

Drug/Important Bio-Agent (IBA)

20Folic Acid (Vitamin M)FDA LinkGeneric
01/2019 - 03/2005
7Pharmaceutical PreparationsIBA
01/2020 - 09/2007
5EC145IBA
03/2014 - 05/2007
4LigandsIBA
01/2019 - 12/2006
3Fluorescein (Funduscein)FDA LinkGeneric
01/2019 - 09/2007
3Fluorescein-5-isothiocyanate (FITC)IBA
01/2019 - 12/2006
3EC0305IBA
06/2017 - 12/2008
3tubulysin BIBA
06/2017 - 12/2008
3HaptensIBA
09/2009 - 12/2006
3Biological ProductsIBA
09/2007 - 07/2005
2Chimeric Antigen ReceptorsIBA
10/2021 - 01/2019
2AlkaloidsIBA
03/2014 - 02/2011
2AminopterinIBA
01/2014 - 04/2011
2EC 0746IBA
01/2014 - 04/2011
2Mitomycin (Mitomycin-C)FDA LinkGeneric
08/2006 - 07/2005
1Folate Receptor 2IBA
10/2021
1InterleukinsIBA
10/2021
1Interleukin-6 (Interleukin 6)IBA
10/2021
1DNA (Deoxyribonucleic Acid)IBA
01/2020
1isothiocyanic acidIBA
01/2019
1EC0531IBA
06/2017
1EC0565IBA
07/2015
1Retinaldehyde (Retinal)IBA
01/2014
1ArrestinIBA
01/2014
1Myelin Basic ProteinIBA
01/2014
1Etanercept (Enbrel)FDA Link
04/2011
1Methotrexate (Mexate)FDA LinkGeneric
04/2011
1EC 0489IBA
02/2011
1EC0225IBA
09/2007
1Immunoglobulin E (IgE)IBA
09/2007
1CytokinesIBA
09/2007
1Glutamic Acid (Glutamate)FDA Link
09/2007
1Therapeutic UsesIBA
07/2007
1Blocking AntibodiesIBA
12/2006
1Neoplasm Antigens (Tumor Antigens)IBA
12/2006
1AntibodiesIBA
12/2006
1HydrazonesIBA
08/2006
1AcidsIBA
08/2006
1Paclitaxel (Taxol)FDA LinkGeneric
08/2006
1AmidesIBA
08/2006
1DisulfidesIBA
08/2006

Therapy/Procedure

11Therapeutics
10/2021 - 03/2005
3Immunotherapy
09/2009 - 12/2006
2Drug Therapy (Chemotherapy)
01/2019 - 08/2006
1Duration of Therapy
12/2006